Glycosides: These are sugar molecules that are bonded with a particular
functional group. Essentially, they have toxic properties, and protect the
plants from becoming ingested by any predators.
Several ways
these compounds cause problems:
·
Saponins have a fat soluble core and
chains of water-soluble carbohydrates. This compound acts like a detergent,
since it mixes with fat and water forming a soluble complex that can bind with
cholesterol. Once it interacts with the cholesterol molecules dietary
saponins create holes in the surface membrane of the cells which line the gut
(enterocytes), allowing a variety of substances found in the gut to enter the
cell. Meaning any potentially undigested proteins, toxins, bacteria,
carcinogens can enter into the blood and cause an immune response.
Other concerns like increased permeability by destroying the lining of the gut
can create
nutritional deficiencies.
·
Cyanogenetic
Glycosides are found in lima
beans, these compounds are extremely poisonous if eaten raw by turning into
hydrogen cyanide in our
intestines. Fortunately, cooking can destroy this poison. However, your
problems are not over, since cooking converts the hydrogen cyanide into thiocyanate, which has been shown to have goitrogen activity in our organisms.
·
Favism Glycosides are also
lethally toxic substances found in fava beans
that can trigger hemolytic anemia in genetically predisposed individuals shown
to have the genetic defect.
Examples of Foods:
·
Amaranth
·
Quinoa
·
Lima Beans
·
Fava Beans
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